Table 3

Motivating and discouraging factors for children to participate in clinical trials

Motivating factors

- Hopes for improvement of their own behaviour based on experience

With benefit for themselves

With benefit for their families

- Comfort (once a day vs. several times a day)

- Explorative behaviour/sensation seeking

Discouraging factors

- Changes in treatment settings

- Time spent

- Study examinations, especially invasive exams/blood-drawing

Koelch et al. Child and Adolescent Psychiatry and Mental Health 2009 3:2   doi:10.1186/1753-2000-3-2